Enter the world of Graphene Biosensing in SPR with SENSIA!
 
SENSIA is the first Basque initiative to establish a leader company in the field of analytical instrumentation based on SPR (Surface Plasmon Resonance), for life sciences laboratories and environmental measurements.
 
SENSIA is breaking through into the SPR market with the first commercially available graphene biosensors .
 
 
 
The technologies developed by SENSIA are based on SPR (Surface Plasmon Resonance) technology.
SENSIA initially developed a  manual portable multibiosensor system, based on a development performed by Biosensor Group within the National Microelectronics Centre (CNM) of the Spanish National Research Council (CSIC). 
 
Since 2008, SENSIA has been following  an innovative process of machine development and is presently bringing into market a new fully automated,  bi-channel  SPR device, delivering with an unequalled sensitivity, transportability, robustness, and extreme stability, allowing deepen existing conventional SPR techniques into the High–SPR world. Its name: the Indicator (TM).
 
Graphene Biosensing:
Gold biosensors and Graphene coated Biosensors are commercially available and can be indifferently used in the Indicator, opening new paths for Research .

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 Publication:

Highly sensitive detection of DNA hybridization on commercialized graphene coated surface plasmon resonance interfaces

Oleksandr Zagorodko , Jolanda Spadavecchia , Artiz Yanguas , Iban Larroulet , Amaia Pesquera , Amaia Zurutuza , Rabah Boukherroub , and Sabine Szunerits

Anal. Chem., Just Accepted Manuscript

DOI: 10.1021/ac502705n

Publication Date (Web): October 23, 2014

Copyright © 2014 American Chemical Society

Abstract

Strategies employed to interface biomolecules with nanomaterials have advanced considerably in recent years and found practical applications in many different research fields. The construction of nucleic acid modified interfaces together with the label-free detection of hybridization events has been one of the major research focuses in science and technology. In this paper, we demonstrate the high interest of graphene-on-metal surface plasmon resonance (SPR) interfaces for the detection of DNA hybridization events in the attomolar concentration range. The strategy consists on the non-covalent functionalization of graphene coated SPR interfaces with gold nanostars carrying single-stranded DNA (ssDNA). Upon hybridization with its complementary, desorption of the nanostructures takes place and thus enables the sensitive detection of the DNA hybridization event. The DNA sensor exhibits a detection limit of ≈500 aM for complementary DNA with a linear dynamic range up to 10-8 M. This label-free DNA detection platform should spur off new interest towards the use of commercially available graphene-coated SPR interfaces.

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                                 Copyright © 2014 SENSIA